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Schakelaar JH. Repeated memory loss. Huisarts Wet 2010;53(2):111-2. This clinical lesson describes a 54-year-old man who experienced two episodes of transient global amnesia in 2 years. Transient global amnesia is a classic neurological picture with a low incidence. It usually disappears within 24 hours without residual signs and seldom recurs, but patients and their friends and relatives are often concerned that it is a stroke. The general practitioner can make the diagnosis based on seven criteria established from the history and physical examination and with knowledge of the differential diagnosis. If there is diagnostic uncertainty about this relatively rare disorder, a neurologist should be consulted.